Product Description
- In the synthesis of 4-substituted phenyl derivatives of 1,2,4-triazolidindiones (urazoles).
- In the solid-phase synthesis of 3-aryl-2,4-quinazolinedione derivatives with potent anti-cancer property.
High Purity and Reliable PerformanceThis industrial-grade 4-nitrophenyl chloroformate delivers consistent results owing to its 99% purity. Its physical stability, low loss on drying (0.02 w/w), and remarkable solubility make it a top choice for pharmaceutical and fine chemical industries, especially in intermediary processes for drug synthesis.
Versatile Applications in Pharma and IndustryAs a key pharmaceutical intermediate, 4-nitrophenyl chloroformate is integral to the production of Ritonavir. Its adaptable profile suits various chemical syntheses, ensuring efficiency and reliability in both small-scale research and large-scale manufacturing environments.
Safe Storage and HandlingFor optimal quality retention, 4-nitrophenyl chloroformate should be stored in a freezer. This helps preserve its shelf life of 12 months and prevents degradation. Strict compliance with safety protocols is recommended when handling this compound in powder form.
FAQs of 4-nitrophenyl chloroformate:
Q: How does 4-nitrophenyl chloroformate support pharmaceutical synthesis?
A: 4-nitrophenyl chloroformate acts as an essential intermediate in the synthesis of pharmaceuticals such as Ritonavir, facilitating efficient coupling reactions and improving yield and purity in finished products.
Q: What is the recommended storage method for this compound?
A: It should be stored in a freezer to maintain its stability and prolong its shelf life for up to 12 months, safeguarding its chemical integrity for industrial or research use.
Q: Where can I source 4-nitrophenyl chloroformate in India?
A: This compound is available through reputable distributors, exporters, suppliers, and manufacturers in India, who supply both domestic and international customers.
Q: When should I use 4-nitrophenyl chloroformate in pharmaceutical production?
A: Employ this intermediate during the chemical synthesis phase of medications such as Ritonavir, where its high purity and reactivity are necessary for successful results.
Q: What are the physical characteristics of 4-nitrophenyl chloroformate?
A: It presents as an off-white to beige or light yellow powder, has a melting point of 78-81C, and a boiling point between 159-162C at 25 hPa, with notable solubility in chloroform and ethyl acetate.
Q: How does using 4-nitrophenyl chloroformate benefit industrial processes?
A: Its stable structure, high purity, and predictable performance help ensure consistent quality and efficiency in industrial chemical production and pharmaceutical manufacturing.
Q: What is the process for safe handling of this powder?
A: Follow established safety protocols including wearing protective equipment and avoiding exposure, as well as maintaining storage in a controlled, cool environment such as a freezer to reduce risks.